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Prion diseases are transmissible neurodegenerative disorders characterized by the accumulation in the CNS of the protease-resistant prion protein a structurally misfolded isoform of its physiological counterpart.84 2. cannabidiol dravet syndrome Anti-inflammatory action In 2000 a few previous reports showing that CBD can modulate tumor necrosis factor in vitro and suppress chemokine production by a human B cell85-87 motivated the study of CBD as a therapeutic agent in
collagen-induced arthritis a model for rheumatoid arthritis.88 This model is based on immunizing mice with type-II collagen. CBD administered i.