These lines of evidence led to several investigations of a possible antipsychotic action of CBD. As a first step to investigate antipsychotic-like properties of CBD in animal models the drug was compared to haloperidol in rats.60 Both drugs reduced the apomorphine-induced stereotyped behavior (such as sniffing and biting) in a dose-related manner. Even though these drugs also increased the plasma level of prolactine
CBD needs higher doses (120 and 240 mg/kg) to show such an effect.
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Without this review the FDA cannot determine whether a drug product is safe and effective. It also cannot ensure that a drug product meets appropriate quality standards. For certain drugs that have not been approved by the FDA such as marijuana the lack of FDA approval and oversight means that the purity and potency of the drug may vary considerably. As with other drugs that are not approved by the FDA the agency works closely with the medical and patient communities and our federal partners when cbd oil etsy necessary to allow access to experimental treatments through the expanded access provisions described in the FDA’s statute and regulations. The FDA’s expanded access provisions are designed to facilitate the availability of investigational products to patients with serious diseases or conditions when there is no comparable or satisfactory alternative therapy available either because the patients have exhausted treatment with or are intolerant of approved therapies or when the patients are not eligible for an ongoing clinical trial.
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